Selected publications
Wang, F., Ding, P., Liang, X., Ding, X., Brandt, C. B., Sjöstedt, E., Zhu, J., Bolund, S., Zhang, L., de Rooij, L., Luo, L., Wei, Y., Zhao, W., Lv, Z., Haskó, J., Li, R., Qin, Q., Jia, Y., Wu, W., Yuan, Y., … Luo, Y. (2022). Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level. Nature communications, 13 (1), 3620. doi.org/10.1038/s41467-022-31388-z
Noer JB, Hørsdal OK, Xiang X, Luo Y, Regenberg B. Extrachromosomal circular DNA in cancer: history, current knowledge, and methods. Trends Genet. 2022 Mar 8:S0168-9525(22)00034-8. doi: 10.1016/j.tig.2022.02.007. Epub ahead of print. PMID: 35277298. (This review provides a comprehensive summary of the eccDNA and its roles in cancers.)
Corsi GI, Qu K, Alkan F, Pan X, Luo Y, Gorodkin J. CRISPR/Cas9 gRNA activity depends on free energy changes and on the target PAM context. Nat Commun. 2022 May 30;13(1):3006. doi: 10.1038/s41467-022-30515-0. PMID: 35637227; PMCID: PMC9151727.
Karlsson M, Sjöstedt E, Oksvold P, Sivertsson Å, Huang J, Álvez MB, Arif M, Li X, Lin L, Yu J, Ma T, Xu F, Han P, Jiang H, Mardinoglu A, Zhang C, von Feilitzen K, Xu X, Wang J, Yang H, Bolund L, Zhong W, Fagerberg L, Lindskog C, Pontén F, Mulder J, Luo Y, Uhlen M. Genome-wide annotation of protein-coding genes in pig. BMC Biol. 2022 Jan 25;20(1):25. doi: 10.1186/s12915-022-01229-y. PMID: 35073880; PMCID: PMC8788080. (The first body-wide classification of protein coding gene expression in pig tissues and organs)
Xiang X, Corsi GI, Anthon C, Qu K, Pan X, Liang X, Han P, Dong Z, Liu L, Zhong J, Ma T, Wang J, Zhang X, Jiang H, Xu F, Liu X, Xu X, Wang J, Yang H, Bolund L, Church GM, Lin L, Gorodkin J, Luo Y. Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning. Nat Commun. 2021 May 28;12(1):3238. doi: 10.1038/s41467-021-23576-0. PMID: 34050182; PMCID: PMC8163799. (This study reports the CRISPRTRAP-seq method for high throughput quantification of CRISPR gRNA activity in cells. The study also reported the generation of new deep learning based tool, CRISPRon, for prediction of CRISPR on-target targeting activity.)
Karlsson M, Zhang C, Méar L, Zhong W, Digre A, Katona B, Sjöstedt E, Butler L, Odeberg J, Dusart P, Edfors F, Oksvold P, von Feilitzen K, Zwahlen M, Arif M, Altay O, Li X, Ozcan M, Mardinoglu A, Fagerberg L, Mulder J, Luo Y, Ponten F, Uhlén M, Lindskog C. A single-cell type transcriptomics map of human tissues. Sci Adv. 2021 Jul 28;7(31):eabh2169. doi: 10.1126/sciadv.abh2169. PMID: 34321199; PMCID: PMC8318366. (A single cell type gene expression atlas in human tissues. This study integrate single cell RNA sequencing results to classify the gene expression specificity in single cell type levels)
Sjöstedt E, Zhong W, Fagerberg L, Karlsson M, Mitsios N, Adori C, Oksvold P, Edfors F, Limiszewska A, Hikmet F, Huang J, Du Y, Lin L, Dong Z, Yang L, Liu X, Jiang H, Xu X, Wang J, Yang H, Bolund L, Mardinoglu A, Zhang C, von Feilitzen K, Lindskog C, Pontén F, Luo Y, Hökfelt T, Uhlén M, Mulder J. An atlas of the protein-coding genes in the human, pig, and mouse brain. Science. 2020 Mar 6;367(6482):eaay5947. doi: 10.1126/science.aay5947. PMID: 32139519. (This study reported the first systematic classification of gene expression specificity and distribution of all protein-coding genes in the mouse, pig and human brain.)
Kalucka J, de Rooij LPMH, Goveia J, Rohlenova K, Dumas SJ, Meta E, Conchinha NV, Taverna F, Teuwen LA, Veys K, García-Caballero M, Khan S, Geldhof V, Sokol L, Chen R, Treps L, Borri M, de Zeeuw P, Dubois C, Karakach TK, Falkenberg KD, Parys M, Yin X, Vinckier S, Du Y, Fenton RA, Schoonjans L, Dewerchin M, Eelen G, Thienpont B, Lin L, Bolund L, Li X, Luo Y, Carmeliet P. Single-Cell Transcriptome Atlas of Murine Endothelial Cells. Cell. 2020 Feb 20;180(4):764-779.e20. doi: 10.1016/j.cell.2020.01.015. Epub 2020 Feb 13. PMID: 32059779. (This study reported the first investigation of EC heterogeneity in mouse tissues/organs using single cell transcriptome analysis)
Niu D, Wei HJ, Lin L, George H, Wang T, Lee IH, Zhao HY, Wang Y, Kan Y, Shrock E, Lesha E, Wang G, Luo Y, Qing Y, Jiao D, Zhao H, Zhou X, Wang S, Wei H, Güell M, Church GM, Yang L. Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9. Science. 2017 Sep 22;357(6357):1303-1307. doi: 10.1126/science.aan4187. Epub 2017 Aug 10. PMID: 28798043; PMCID: PMC5813284. (The first PERV inactivated pigs were generated by CRISPR and cloning.)
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Cavazza, A., Molina-Estévez, F. J., Reyes, Á. P., Ronco, V., Naseem, A., Malenšek, Š., Pečan, P., Santini, A., Heredia, P., Aguilar-González, A., Boulaiz, H., Ni, Q., Cortijo-Gutierrez, M., Pavlovic, K., Herrera, I., de la Cerda, B., Garcia-Tenorio, E. M., Richard, E., Granados-Principal, S. ... Benabdellah, K. (2025). Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group. Molecular Therapy Nucleic Acids, 36(1), Article 102457. https://doi.org/10.1016/j.omtn.2025.102457
Han, B., Li, H., Zheng, W., Zhang, Q., Chen, A., Zhu, S., Shi, T., Wang, F., Zou, D., Song, Y., Ye, W., Du, A., Fu, Y., Jia, M., Bai, Z., Yuan, Z., Liu, W., Tuo, W., Hope, J. C. ... Sun, D. (2025). A multi-tissue single-cell expression atlas in cattle. Nature Genetics, 57(10), 2546-2561. https://doi.org/10.1038/s41588-025-02329-5
Yuan, H., Song, C., Xu, H., Sun, Y., Anthon, C., Bolund, L., Lin, L., Benabdellah, K., Lee, C., Hou, Y., Gorodkin, J. & Luo, Y. (2025). An Overview and Comparative Analysis of CRISPR-SpCas9 gRNA Activity Prediction Tools. The CRISPR Journal, 8(2), 89-104. https://doi.org/10.1089/crispr.2024.0058
Shi, M., Méar, L., Karlsson, M., Álvez, M. B., Digre, A., Schutten, R., Katona, B., Vuu, J., Lindström, E., Hikmet, F., Jin, H., Yuan, M., Li, X., Yang, H., Song, X., Sjöstedt, E., Edfors, F., Oksvold, P., von Feilitzen, K. ... Zhang, C. (2025). A resource for whole-body gene expression map of human tissues based on integration of single cell and bulk transcriptomics. Genome Biology, 26(1), 152. Article 152. https://doi.org/10.1186/s13059-025-03616-4
García-Rodríguez, J. L., Korsgaard, U., Vissing, S. M., Paasch, T. P., Semenova, M., Vendelbo, S. L., Jensby, E. F., Williams, H. L., Salachan, P. V., Brandt, C. B., Hanimann, J., Lin, L., Zlobec, I., Sørensen, K. D., Kjems, J., Hager, H. & Kristensen, L. S. (2025). Cancer-associated fibroblasts shape the formation of budding cancer cells at the invasive front of human colorectal cancer. Communications Biology, 8(1), Article 1345. https://doi.org/10.1038/s42003-025-08799-x
Nadukkandy, A. S., Kalaiselvan, S., Lin, L. & Luo, Y. (2025). Clinical application of single-cell RNA sequencing in disease and therapy. Clinical and Translational Medicine, 15(11), e70512. https://doi.org/10.1002/ctm2.70512
Brorson, J., Lin, L., Wang, J., Bæk, A., Billeskov, T. B., Thybo, F. F., Just, J., Haskó, J., Ravn, C., Hansen, R. L., Bue, M., Jørgensen, J. O. L., Luo, Y., Jessen, N. & Farup, J. (2025). Complementing muscle regeneration-fibro-adipogenic progenitor and macrophage-mediated repair of elderly human skeletal muscle. Nature Communications, 16(1), Article 5233. https://doi.org/10.1038/s41467-025-60627-2
Sun, Y., Qu, K., Corsi, G. I., Anthon, C., Pan, X., Xiang, X., Jensen, L. J., Lin, L., Luo, Y. & Gorodkin, J. (2025). Deep learning models simultaneously trained on multiple datasets improve base-editing activity prediction. Nature Communications, 16(1), Article 9821. https://doi.org/10.1038/s41467-025-65200-5
AlZaim, I., Hassan, M. N., Schröter, M., Mannino, L., Dragicevic, K., Sjogaard, M. B., Festa, J., Dokshokova, L., Weinbrenner, S., Tardajos Ayllon, B., Hansen, B., Rasmussen, R. K., Christensen, J. N., Wagman, O., Schipper, R., Cai, M., Dheedene, W., Bohn, A. B., Farup, J. ... Kalucka, J. (2025). Defining the vascular niche of human adipose tissue across metabolic states. bioRxiv. https://doi.org/10.1101/2024.09.22.610444
Liang, X., Arrey, G., Qin, Y., Álvarez-González, L., Hariprakash, J. M., Ma, J., Holt, S., Han, P., Luo, Y., Li, H., Ruiz-Herrera, A., Pilegaard, H. & Regenberg, B. (2025). EccDNA atlas in male mice reveals features protecting genes against transcription-induced eccDNA formation. Nature Communications, 16(1), 1872. Article 1872. https://doi.org/10.1038/s41467-025-57042-y
Li, C., Lv, W., He, Z., Pan, X., Zeng, Y., Mulder, J., Sjöstedt, E., Huang, Z., Liu, W., Xu, L., Eisenberg, E., Lin, L., Hansen, J. B., Huang, J. & Luo, Y. (2025). Landscape of A-I RNA editing in mouse, pig, macaque, and human brains. Nucleic Acids Research, 53(11), Article gkaf534. https://doi.org/10.1093/nar/gkaf534
Ahlgreen, O. A., Hansen, M. W., Baake, J., Hybel, T. E., Rossi, R., Lai, X., Sankaranarayanan, I., Pold, J. A., Lin, L., Reinert, L., Paludan, S. R., Price, T. J., Pallesen, L. T. & Vægter, C. B. (2025). Mapping Satellite Glial Cell Heterogeneity Reveals Distinct Spatial Organization and Implies Functional Diversity in the Dorsal Root Ganglion. Advanced Science, e11569. Advance online publication. https://doi.org/10.1002/advs.202511569
Zeng, Y., Lv, W., Tao, H., Li, C., Jiang, S., Liang, Y., Chen, C., Yu, T., Li, Y., Wu, S., Cui, X., Liang, N., Wang, P., Xu, H., Dong, J., Teng, H., Chen, K., Mu, K., Fan, T. ... Han, P. (2025). Mapping the chromothripsis landscape in urothelial carcinoma unravels great intratumoral and intertumoral heterogeneity. iScience, 28(1), 111510. Article 111510. https://doi.org/10.1016/j.isci.2024.111510
Fonager, S. V., Winther, G., Weber, Y. C. L., Wittenborn, T. R., Kastberg, K. S., Terczyńska-Dyla, E., Jensen, L., Hansen, L. A., Carroll, M. C., Luo, Y., Lin, L. & Degn, S. E. (2025). Maternal imprinting of autoreactivity in a murine model of systemic lupus erythematosus. Brain, Behavior, and Immunity, 129, 921-934. https://doi.org/10.1016/j.bbi.2025.07.025
Luo, Y. & COST Action CA21113 Members (2025). Proceedings of the second annual meeting of GenE-HumDi (COST Action 21113). Frontiers in Genome Editing, 7, Article 1667329. https://doi.org/10.3389/fgeed.2025.1667329
Yuan, H., Song, Z., Sun, X.-Q., Song, C., Guo, L., Zhang, Q., Luo, Y., Yuan, C., Gao, J. & Jia, X. (2025). Profiling the cell diversity and tissue structure of aqueous humor circulatory system in human eyes using spatial single-cell RNA sequencing. Genes & diseases, 12(1), 101304. Article 101304. https://doi.org/10.1016/j.gendis.2024.101304
Koning, M., Dumas, S. J., Meta, E., Lievers, E., de Graaf, A. M. A., Borri, M., Nai Chung Tong, L. J., Liang, X., Liu, P., Chen, F., Lin, L., Luo, Y., Carmeliet, P., van den Berg, C. W. & Rabelink, T. J. (2025). Single cell transcriptomics of human kidney organoid endothelium reveals vessel growth processes and arterial maturation upon transplantation. npj Regenerative Medicine, 10(1), Article 32. https://doi.org/10.1038/s41536-025-00418-x
Lv, W., Zeng, Y., Li, C., Liang, Y., Tao, H., Zhu, Y., Sui, X., Li, Y., Jiang, S., Gao, Q., Rodriguez-Fos, E., Prasad, G., Wang, Y., Zhou, R., Xu, Z., Pan, X., Chen, L., Xiang, X., Teng, H. ... Han, P. (2025). Spatial-Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment. Cancer Discovery, 15(6), 1225-1246. https://doi.org/10.1158/2159-8290.CD-24-1532
Hansen, L. M. B., Dam, V. S., Guldbrandsen, H. Ø., Staehr, C., Pedersen, T. M., Kalucka, J. M., Beck, H. C., Postnov, D., Lin, L. & Matchkov, V. (2025). Spatial Transcriptomics and Proteomics Profiling After Ischemic Stroke Reperfusion: Insights Into Vascular Alterations. Stroke, 56(4), 1036-1047. https://doi.org/10.1161/STROKEAHA.124.048085
Gultom, M., Lin, L., Brandt, C. B., Milusev, A., Despont, A., Shaw, J., Döring, Y., Luo, Y. & Rieben, R. (2025). Sustained Vascular Inflammatory Effects of SARS-CoV-2 Spike Protein on Human Endothelial Cells. Inflammation, 48(4), 2531–2547. https://doi.org/10.1007/s10753-024-02208-x
Ding, X., Lai, X., Klaestrup, I. H., Jensen, S. R. N., Nielsen, M. M., Thorsen, K., Romero-Ramos, M., Luo, Y., Lin, L., Reinert, L. S. & Paludan, S. R. (2025). Temporally resolved single-cell RNA sequencing reveals protective and pathological responses during herpes simplex virus CNS infection. Journal of Neuroinflammation, 22(1), Article 146. https://doi.org/10.1186/s12974-025-03471-x
FarmGTEx Consortium (2025). The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project. Nature Genetics, 57(4), 786-796. Article 604. https://doi.org/10.1038/s41588-025-02121-5
The PigGTEx Consortium (2024). A compendium of genetic regulatory effects across pig tissues. Nature Genetics, 56(1), 112-123. https://doi.org/10.1038/s41588-023-01585-7
Ma, W., Huang, J., Cai, B., Shao, M., Yu, X., Kjær, M. B., Lv, M., Zhong, X., Xu, S., Zhan, B., Li, Q., Huang, Q., Ma, M., Cheng, L., Luo, Y., Grønbæk, H., Zhou, X. & Lin, L. (2024). A gene-based clustering approach reveals QSOX1/IL1RAP as promising biomarkers for the severity of non-alcoholic fatty liver disease. https://doi.org/10.1101/2023.07.26.23293038
Gao, P., Li, S., Dong, Z., Luo, Y., Zhang, X., Han, L., Peng, S., Shen, J., Xu, F. & Deng, Z. (2024). A plasma-derived exosomal microRNA signature by small RNA sequencing for early detection of postmenopausal osteoporosis. Clinical and Translational Medicine, 14(4), Article e1637. https://doi.org/10.1002/ctm2.1637
Cham, L. B., Lin, L., Tolstrup, M. & Søgaard, O. S. (2024). Development of single-cell transcriptomic atlas of human plasmacytoid dendritic cells from people with HIV-1. STAR Protocols, 5(1), 102777. Article 102777. https://doi.org/10.1016/j.xpro.2023.102777
Lv, W., Pan, X., Han, P., Wu, S., Zeng, Y., Wang, Q., Guo, L., Xu, M., Qi, Y., Deng, L., Xu, Z., Li, C., Yu, T., Cui, X., Teng, H., Xiang, C., Tan, H., Li, Y., Liang, N. ... Luo, Y. (2024). Extrachromosomal circular DNA orchestrates genome heterogeneity in urothelial bladder carcinoma. Theranostics, 14(13), 5102-5122. https://doi.org/10.7150/thno.99563
Huang, F., Lyu, B., Xie, F., Li, F., Xing, Y., Han, Z., Lai, J., Ma, J., Zou, Y., Zeng, H., Xu, Z., Gao, P., Luo, Y., Bolund, L., Tong, G. & Fengping, X. (2024). From gut to liver: unveiling the differences of intestinal microbiota in NAFL and NASH patients. Frontiers in Microbiology, 15, Article 1366744. https://doi.org/10.3389/fmicb.2024.1366744
Recknagel, H., Močivnik, L., Zakšek, V., Luo, Y., Kostanjšek, R. & Trontelj, P. (2024). Generation of genome-wide SNP markers from minimally invasive sampling in endangered animals and applications in species ecology and conservation. Molecular Ecology Resources, 24(7), Article e13995. https://doi.org/10.1111/1755-0998.13995
Cömert, C., Kjær-Sørensen, K., Hansen, J., Carlsen, J., Just, J., Meaney, B. F., Østergaard, E., Luo, Y., Oxvig, C., Schmidt-Laursen, L., Palmfeldt, J., Fernandez-Guerra, P. & Bross, P. (2024). HSP60 chaperone deficiency disrupts the mitochondrial matrix proteome and dysregulates cholesterol synthesis. Molecular Metabolism, 88, Article 102009. https://doi.org/10.1016/j.molmet.2024.102009
Gál, Z., Boukoura, S., Oxe, K. C., Badawi, S., Nieto, B., Korsholm, L. M., Geisler, S. B., Dulina, E., Rasmussen, A. V., Dahl, C., Lv, W., Xu, H., Pan, X., Arampatzis, S., Stratou, D.-E., Galanos, P., Lin, L., Guldberg, P., Bartek, J. ... Larsen, D. H. (2024). Hyper-recombination in ribosomal DNA is driven by long-range resection-independent RAD51 accumulation. Nature Communications, 15(1), Article 7797. https://doi.org/10.1038/s41467-024-52189-6
Lebas, M., Chinigò, G., Courmont, E., Bettaieb, L., Machmouchi, A., Goveia, J., Beatovic, A., Van Kerckhove, J., Robil, C., Angulo, F. S., Vedelago, M., Errerd, A., Treps, L., Gao, V., Delgado De la Herrán, H. C., Mayeuf-Louchart, A., L'homme, L., Chamlali, M., Dejos, C. ... Cantelmo, A. R. (2024). Integrated single-cell RNA-seq analysis reveals mitochondrial calcium signaling as a modulator of endothelial-to-mesenchymal transition. Science Advances, 10(32), eadp6182. Article adp6182. https://doi.org/10.1126/sciadv.adp6182
Madan, E., Palma, A. M., Vudatha, V., Kumar, A., Bhoopathi, P., Wilhelm, J., Bernas, T., Martin, P. C., Bilolikar, G., Gogna, A., Peixoto, M. L., Dreier, I., Araujo, T. F., Garre, E., Gustafsson, A., Dorayappan, K. D. P., Mamidi, N., Sun, Z., Yekelchyk, M. ... Gogna, R. (2024). Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells. Nature Biotechnology, Article e13714. Advance online publication. https://doi.org/10.1038/s41587-024-02453-3
Zhou, M., Lv, W., Han, P., Sun, K., Hao, Z., Gao, L., Xu, Y., Xu, Z., Shao, S., Ma, S., Guo, Q., Zhang, H., Liu, K., Yang, F., Yuan, Z., Wu, G., Yu, C., Luo, Y., Yao, Z. & Zhao, J. (2024). Plasma extrachromosomal circular DNA as a potential diagnostic biomarker for nodular thyroid disease. Clinical and Translational Medicine, 14(6), e1740. https://doi.org/10.1002/ctm2.1740
Cham, L. B., Rosas-Umbert, M., Lin, L., Tolstrup, M. & Søgaard, O. S. (2024). Single-Cell Analysis Reveals That CD47 mRNA Expression Correlates with Immune Cell Activation, Antiviral Isgs, and Cytotoxicity. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 58(4), 322-335. https://doi.org/10.33594/000000715
Chai, C., Liang, L., Mikkelsen, N. S., Wang, W., Zhao, W., Sun, C., Bak, R. O., Li, H., Lin, L., Wang, F. & Luo, Y. (2024). Single-cell transcriptome analysis of epithelial, immune, and stromal signatures and interactions in human ovarian cancer. Communications Biology, 7(1), 131. Article 131. https://doi.org/10.1038/s42003-024-05826-1
Liang, L., Chai, C., Liu, A., Nadukkandy, A. S., Kalaiselvan, S., Brandt, C. B., Zhao, W., Li, H., Lin, L., Wu, J. & Luo, Y. (2024). Single-cell transcriptome analysis reveals reciprocal epithelial and endothelial cell evolution in ovarian cancer. iScience, 27(12), Article 111417. https://doi.org/10.1016/j.isci.2024.111417
Skorda, A., Lauridsen, A. R., Wu, C., Huang, J., Mrackova, M., Winther, N. I., Jank, V., Sztupinszki, Z., Strauss, R., Bilgin, M., Maeda, K., Liu, B., Luo, Y., Jäättelä, M. & Kallunki, T. (2023). Activation of invasion by oncogenic reprogramming of cholesterol metabolism via increased NPC1 expression and macropinocytosis. Oncogene, 42(33), 2495-2506. https://doi.org/10.1038/s41388-023-02771-x
Faienza, F., Polverino, F., Rajendraprasad, G., Milletti, G., Hu, Z., Colella, B., Gargano, D., Strappazzon, F., Rizza, S., Vistesen, M. V., Luo, Y., Antonioli, M., Cianfanelli, V., Ferraina, C., Fimia, G. M., Filomeni, G., De Zio, D., Dengjel, J., Barisic, M. ... Cecconi, F. (2023). AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation. Cellular and molecular life sciences : CMLS, 80(9), Article 251. https://doi.org/10.1007/s00018-023-04878-6
Fahlquist-Hagert, C., Wittenborn, T. R., Terczyńska-Dyla, E., Kastberg, K. S., Yang, E., Rallistan, A. N., Markett, Q. R., Winther, G., Fonager, S., Voss, L. F., Pedersen, M. K., van Campen, N., Ferapontov, A., Jensen, L., Huang, J., Nieland, J. D., van der Poel, C. E., Palmfeldt, J., Carroll, M. C. ... Degn, S. E. (2023). Antigen presentation by B cells enables epitope spreading across an MHC barrier. Nature Communications, 14(1), Article 6941. https://doi.org/10.1038/s41467-023-42541-7
Liu, B., Chen, R., Zhang, Y., Huang, J., Luo, Y., Rosthøj, S., Zhao, C. & Jäättelä, M. (2023). Cationic amphiphilic antihistamines inhibit STAT3 via Ca2+-dependent lysosomal H+ efflux. Cell Reports, 42(2), Article 112137. https://doi.org/10.1016/j.celrep.2023.112137
Zhao, X., Qu, K., Curci, B., Yang, H., Bolund, L., Lin, L. & Luo, Y. (2023). Comparison of In-Frame Deletion, Homology-Directed Repair, and Prime Editing-Based Correction of Duchenne Muscular Dystrophy Mutations. Biomolecules, 13(5), Article 870. https://doi.org/10.3390/biom13050870
Berggreen, A. H., Petersen, J. L., Lin, L., Benabdellah, K. & Luo, Y. (2023). CRISPR delivery with extracellular vesicles: Promises and challenges. Journal of Extracellular Biology, 2(9), e111. Article e111. https://doi.org/10.1002/jex2.111
Porter, R., Černoša, A., Fernández-Sanmartín, P., Cortizas, A. M., Aranda, E., Luo, Y., Zalar, P., Podlogar, M., Gunde-Cimerman, N. & Gostinčar, C. (2023). Degradation of polypropylene by fungi Coniochaeta hoffmannii and Pleurostoma richardsiae. Microbiological Research, 277, Article 127507. https://doi.org/10.1016/j.micres.2023.127507
Huang, J., Lin, Q., Fei, H., He, Z., Xu, H., Li, Y., Qu, K., Han, P., Gao, Q., Li, B., Liu, G., Zhang, L., Hu, J., Zuo, E., Luo, Y., Ran, Y., Qiu, J.-L., Zhao, K. T. & Gao, C. (2023). Discovery of deaminase functions by structure-based protein clustering. Cell, 186(15), 3182-3195.e14. https://doi.org/10.1016/j.cell.2023.05.041
Neldeborg, S., Soerensen, J. F., Møller, C. T., Bill, M., Gao, Z., Bak, R. O., Holm, K., Sorensen, B., Nyegaard, M., Luo, Y., Hokland, P., Stougaard, M., Ludvigsen, M. & Holm, C. K. (2023). Dual intron-targeted CRISPR-Cas9-mediated disruption of the AML RUNX1-RUNX1T1 fusion gene effectively inhibits proliferation and decreases tumor volume in vitro and in vivo. Leukemia, 37(9), 1792-1801. https://doi.org/10.1038/s41375-023-01950-9
Xiao, J., Wang, F., Hu, X., Li, D., Liu, G., Xu, Q., Chen, C., Xiang, H., Dong, X., Zhu, L., Yang, D., Gao, Y., Wang, M., Luo, Y., Chao, C. C., Li, G. & Guo, Q. (2023). Engineering In Vitro Organ-Structured Tumor Model for Evaluating Neoantigen-Specific T Cell Responses in Hepatocellular Carcinoma. Advanced Materials Interfaces, 10(24), Article 2300155. https://doi.org/10.1002/admi.202300155
Larsen, T. V., Dybdal, N., Daugaard, T. F., Lade-Keller, J., Lin, L., Sorensen, B. S. & Nielsen, A. L. (2023). Examination of the Functional Relationship between PD-L1 DNA Methylation and mRNA Expression in Non-Small-Cell Lung Cancer. Cancers, 15(6), Article 1909. https://doi.org/10.3390/cancers15061909
Rizza, S., Di Leo, L., Pecorari, C., Giglio, P., Faienza, F., Montagna, C., Maiani, E., Puglia, M., Bosisio, F. M., Petersen, T. S., Lin, L., Rissler, V., Viloria, J. S., Luo, Y., Papaleo, E., De Zio, D., Blagoev, B. & Filomeni, G. (2023). GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation. Cell Reports, 42(1), Article 111997. https://doi.org/10.1016/j.celrep.2023.111997
Brandt, C. B., Fonager, S. V., Haskó, J., Helmig, R. B., Degn, S., Bolund, L., Jessen, N., Lin, L. & Luo, Y. (2023). HIF1A Knockout by Biallelic and Selection-Free CRISPR Gene Editing in Human Primary Endothelial Cells with Ribonucleoprotein Complexes. Biomolecules, 13(1), Article 23. https://doi.org/10.3390/biom13010023
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