The human Ovarian Cancer Single Cell Gene Expression database (OvCdb) contains currated and integrated gene expression profile from over half a million cells.
A single cell transcriptome Atlas of pig organs.
Wang, F., Ding, P., Liang, X., Ding, X., Brandt, C. B., Sjöstedt, E., Zhu, J., Bolund, S., Zhang, L., de Rooij, L., Luo, L., Wei, Y., Zhao, W., Lv, Z., Haskó, J., Li, R., Qin, Q., Jia, Y., Wu, W., Yuan, Y., … Luo, Y. (2022). Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level. Nature communications, 13
(1), 3620. doi.org/10.1038/s41467-022-31388-z
This database is created to enable the exploration of gene expression changes at the single cells level for conditions related to xenotransplantation applications.
Version 2022v1 contains single cell RNA sequencing of endothelial cells from WT and 4KO pig kidneys perfused with human blood for six hours. The 4KO genetically modified pigs lack three xenoantigens and the MHC class I.
Citation: updated later.
A deep-learning based CRISPR gRNA design and enhanced on-target efficiency prediction tool.
Citation: Nat Commun. 2021 May 28;12(1):3238.
A spatial gene expression atlas of mouse models (UUO) of chronic kidney injury. Coming soon!
A spatial gene expression atlas of human muscle injury and regeneration. Coming soon!