Selected publications
Wang, F., Ding, P., Liang, X., Ding, X., Brandt, C. B., Sjöstedt, E., Zhu, J., Bolund, S., Zhang, L., de Rooij, L., Luo, L., Wei, Y., Zhao, W., Lv, Z., Haskó, J., Li, R., Qin, Q., Jia, Y., Wu, W., Yuan, Y., … Luo, Y. (2022). Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level. Nature communications, 13 (1), 3620. doi.org/10.1038/s41467-022-31388-z
Noer JB, Hørsdal OK, Xiang X, Luo Y, Regenberg B. Extrachromosomal circular DNA in cancer: history, current knowledge, and methods. Trends Genet. 2022 Mar 8:S0168-9525(22)00034-8. doi: 10.1016/j.tig.2022.02.007. Epub ahead of print. PMID: 35277298. (This review provides a comprehensive summary of the eccDNA and its roles in cancers.)
Corsi GI, Qu K, Alkan F, Pan X, Luo Y, Gorodkin J. CRISPR/Cas9 gRNA activity depends on free energy changes and on the target PAM context. Nat Commun. 2022 May 30;13(1):3006. doi: 10.1038/s41467-022-30515-0. PMID: 35637227; PMCID: PMC9151727.
Karlsson M, Sjöstedt E, Oksvold P, Sivertsson Å, Huang J, Álvez MB, Arif M, Li X, Lin L, Yu J, Ma T, Xu F, Han P, Jiang H, Mardinoglu A, Zhang C, von Feilitzen K, Xu X, Wang J, Yang H, Bolund L, Zhong W, Fagerberg L, Lindskog C, Pontén F, Mulder J, Luo Y, Uhlen M. Genome-wide annotation of protein-coding genes in pig. BMC Biol. 2022 Jan 25;20(1):25. doi: 10.1186/s12915-022-01229-y. PMID: 35073880; PMCID: PMC8788080. (The first body-wide classification of protein coding gene expression in pig tissues and organs)
Xiang X, Corsi GI, Anthon C, Qu K, Pan X, Liang X, Han P, Dong Z, Liu L, Zhong J, Ma T, Wang J, Zhang X, Jiang H, Xu F, Liu X, Xu X, Wang J, Yang H, Bolund L, Church GM, Lin L, Gorodkin J, Luo Y. Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning. Nat Commun. 2021 May 28;12(1):3238. doi: 10.1038/s41467-021-23576-0. PMID: 34050182; PMCID: PMC8163799. (This study reports the CRISPRTRAP-seq method for high throughput quantification of CRISPR gRNA activity in cells. The study also reported the generation of new deep learning based tool, CRISPRon, for prediction of CRISPR on-target targeting activity.)
Karlsson M, Zhang C, Méar L, Zhong W, Digre A, Katona B, Sjöstedt E, Butler L, Odeberg J, Dusart P, Edfors F, Oksvold P, von Feilitzen K, Zwahlen M, Arif M, Altay O, Li X, Ozcan M, Mardinoglu A, Fagerberg L, Mulder J, Luo Y, Ponten F, Uhlén M, Lindskog C. A single-cell type transcriptomics map of human tissues. Sci Adv. 2021 Jul 28;7(31):eabh2169. doi: 10.1126/sciadv.abh2169. PMID: 34321199; PMCID: PMC8318366. (A single cell type gene expression atlas in human tissues. This study integrate single cell RNA sequencing results to classify the gene expression specificity in single cell type levels)
Sjöstedt E, Zhong W, Fagerberg L, Karlsson M, Mitsios N, Adori C, Oksvold P, Edfors F, Limiszewska A, Hikmet F, Huang J, Du Y, Lin L, Dong Z, Yang L, Liu X, Jiang H, Xu X, Wang J, Yang H, Bolund L, Mardinoglu A, Zhang C, von Feilitzen K, Lindskog C, Pontén F, Luo Y, Hökfelt T, Uhlén M, Mulder J. An atlas of the protein-coding genes in the human, pig, and mouse brain. Science. 2020 Mar 6;367(6482):eaay5947. doi: 10.1126/science.aay5947. PMID: 32139519. (This study reported the first systematic classification of gene expression specificity and distribution of all protein-coding genes in the mouse, pig and human brain.)
Kalucka J, de Rooij LPMH, Goveia J, Rohlenova K, Dumas SJ, Meta E, Conchinha NV, Taverna F, Teuwen LA, Veys K, García-Caballero M, Khan S, Geldhof V, Sokol L, Chen R, Treps L, Borri M, de Zeeuw P, Dubois C, Karakach TK, Falkenberg KD, Parys M, Yin X, Vinckier S, Du Y, Fenton RA, Schoonjans L, Dewerchin M, Eelen G, Thienpont B, Lin L, Bolund L, Li X, Luo Y, Carmeliet P. Single-Cell Transcriptome Atlas of Murine Endothelial Cells. Cell. 2020 Feb 20;180(4):764-779.e20. doi: 10.1016/j.cell.2020.01.015. Epub 2020 Feb 13. PMID: 32059779. (This study reported the first investigation of EC heterogeneity in mouse tissues/organs using single cell transcriptome analysis)
Niu D, Wei HJ, Lin L, George H, Wang T, Lee IH, Zhao HY, Wang Y, Kan Y, Shrock E, Lesha E, Wang G, Luo Y, Qing Y, Jiao D, Zhao H, Zhou X, Wang S, Wei H, Güell M, Church GM, Yang L. Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9. Science. 2017 Sep 22;357(6357):1303-1307. doi: 10.1126/science.aan4187. Epub 2017 Aug 10. PMID: 28798043; PMCID: PMC5813284. (The first PERV inactivated pigs were generated by CRISPR and cloning.)
Full publications
Sort by:
Date
Faienza, F., Polverino, F., Rajendraprasad, G., Milletti, G., Hu, Z., Colella, B., Gargano, D., Strappazzon, F., Rizza, S., Vistesen, M. V., Luo, Y., Antonioli, M., Cianfanelli, V., Ferraina, C., Fimia, G. M., Filomeni, G., De Zio, D., Dengjel, J., Barisic, M. ... Cecconi, F. (2023). AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation. Cellular and Molecular Life Sciences, 80(9), Article 251. https://doi.org/10.1007/s00018-023-04878-6
Fahlquist-Hagert, C., Wittenborn, T. R., Terczyńska-Dyla, E., Kastberg, K. S., Yang, E., Rallistan, A. N., Markett, Q. R., Winther, G., Fonager, S., Voss, L. F., Pedersen, M. K., van Campen, N., Ferapontov, A., Jensen, L., Huang, J., Nieland, J. D., van der Poel, C. E., Palmfeldt, J., Carroll, M. C. ... Degn, S. E. (2023). Antigen presentation by B cells enables epitope spreading across an MHC barrier. Nature Communications, 14(1), Article 6941. https://doi.org/10.1038/s41467-023-42541-7
Liu, B., Chen, R., Zhang, Y., Huang, J., Luo, Y., Rosthøj, S., Zhao, C. & Jäättelä, M. (2023). Cationic amphiphilic antihistamines inhibit STAT3 via Ca2+-dependent lysosomal H+ efflux. Cell Reports, 42(2), Article 112137. https://doi.org/10.1016/j.celrep.2023.112137
Zhao, X., Qu, K., Curci, B., Yang, H., Bolund, L., Lin, L. & Luo, Y. (2023). Comparison of In-Frame Deletion, Homology-Directed Repair, and Prime Editing-Based Correction of Duchenne Muscular Dystrophy Mutations. Biomolecules, 13(5), Article 870. https://doi.org/10.3390/biom13050870
Berggreen, A. H., Petersen, J. L., Lin, L., Benabdellah, K. & Luo, Y. (2023). CRISPR delivery with extracellular vesicles: Promises and challenges. Journal of Extracellular Biology, 2(9), e111. Article e111. https://doi.org/10.1002/jex2.111
Porter, R., Černoša, A., Fernández-Sanmartín, P., Cortizas, A. M., Aranda, E., Luo, Y., Zalar, P., Podlogar, M., Gunde-Cimerman, N. & Gostinčar, C. (2023). Degradation of polypropylene by fungi Coniochaeta hoffmannii and Pleurostoma richardsiae. Microbiological Research, 277, Article 127507. https://doi.org/10.1016/j.micres.2023.127507
Huang, J., Lin, Q., Fei, H., He, Z., Xu, H., Li, Y., Qu, K., Han, P., Gao, Q., Li, B., Liu, G., Zhang, L., Hu, J., Zuo, E., Luo, Y., Ran, Y., Qiu, J.-L., Zhao, K. T. & Gao, C. (2023). Discovery of deaminase functions by structure-based protein clustering. Cell, 186(15), 3182-3195.e14. https://doi.org/10.1016/j.cell.2023.05.041
Neldeborg, S., Soerensen, J. F., Møller, C. T., Bill, M., Gao, Z., Bak, R. O., Holm, K., Sorensen, B., Nyegaard, M., Luo, Y., Hokland, P., Stougaard, M., Ludvigsen, M. & Holm, C. K. (2023). Dual intron-targeted CRISPR-Cas9-mediated disruption of the AML RUNX1-RUNX1T1 fusion gene effectively inhibits proliferation and decreases tumor volume in vitro and in vivo. Leukemia, 37(9), 1792-1801. https://doi.org/10.1038/s41375-023-01950-9
Xiao, J., Wang, F., Hu, X., Li, D., Liu, G., Xu, Q., Chen, C., Xiang, H., Dong, X., Zhu, L., Yang, D., Gao, Y., Wang, M., Luo, Y., Chao, C. C., Li, G. & Guo, Q. (2023). Engineering In Vitro Organ-Structured Tumor Model for Evaluating Neoantigen-Specific T Cell Responses in Hepatocellular Carcinoma. Advanced Materials Interfaces, 10(24), Article 2300155. https://doi.org/10.1002/admi.202300155
Larsen, T. V., Dybdal, N., Daugaard, T. F., Lade-Keller, J., Lin, L., Sorensen, B. S. & Nielsen, A. L. (2023). Examination of the Functional Relationship between PD-L1 DNA Methylation and mRNA Expression in Non-Small-Cell Lung Cancer. Cancers, 15(6), Article 1909. https://doi.org/10.3390/cancers15061909
Rizza, S., Di Leo, L., Pecorari, C., Giglio, P., Faienza, F., Montagna, C., Maiani, E., Puglia, M., Bosisio, F. M., Petersen, T. S., Lin, L., Rissler, V., Viloria, J. S., Luo, Y., Papaleo, E., De Zio, D., Blagoev, B. & Filomeni, G. (2023). GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation. Cell Reports, 42(1), Article 111997. https://doi.org/10.1016/j.celrep.2023.111997
Brandt, C. B., Fonager, S. V., Haskó, J., Helmig, R. B., Degn, S., Bolund, L., Jessen, N., Lin, L. & Luo, Y. (2023). HIF1A Knockout by Biallelic and Selection-Free CRISPR Gene Editing in Human Primary Endothelial Cells with Ribonucleoprotein Complexes. Biomolecules, 13(1), Article 23. https://doi.org/10.3390/biom13010023
Zhou, X., Rahimi, K., Kjems, J. & Lin, L. (2023). High-resolution RNA isoform variation analysis by combining the advantages of single-cell RNA and nanopore sequencing. 44. Abstract from Neuroscience Day, Aarhus, Denmark.
Liu, H., Guan, L., Deng, M., Bolund, L., Kristiansen, K., Zhang, J., Luo, Y. & Zhang, Z. (2023). Integrative genetic and single cell RNA sequencing analysis provides new clues to the amyotrophic lateral sclerosis neurodegeneration. Frontiers in Neuroscience, 17, Article 1116087. https://doi.org/10.3389/fnins.2023.1116087
Xu, Z., He, J., Han, P., Dai, P., Lv, W., Liu, N., Liu, L., Liu, L., Pan, X., Xiang, X., Li, H., Ge, F., Gao, S., Liao, Z., Luo, Y. & Li, Y. (2023). Plasma extrachromosomal circular DNA is a pathophysiological hallmark of short-term intensive insulin therapy for type 2 diabetes. Clinical and Translational Medicine, 13(10), Article e1437. https://doi.org/10.1002/ctm2.1437
Cavazza, A., Hendel, A., Bak, R. O., Rio, P., Güell, M., Lainšček, D., Arechavala-Gomeza, V., Peng, L., Hapil, F. Z., Harvey, J., Ortega, F. G., Gonzalez-Martinez, C., Lederer, C. W., Mikkelsen, K., Gasiunas, G., Kalter, N., Gonçalves, M. A. F. V., Petersen, J., Garanto, A. ... COST Action CA21113 (2023). Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi. Molecular Therapy Nucleic Acids, 34, 102066. Article 102066. https://doi.org/10.1016/j.omtn.2023.102066, https://doi.org/10.1016/j.omtn.2023.102066
Zeng, Y., Wang, A., Lv, W., Wang, Q., Jiang, S., Pan, X., Wang, F., Yang, H., Bolund, L., Lin, C., Han, P. & Luo, Y. (2023). Recent development of urinary biomarkers for bladder cancer diagnosis and monitoring. Clinical and Translational Discovery, 3(2), Article e183. https://doi.org/10.1002/ctd2.183
Rovsing, A. B., Thomsen, E. A., Nielsen, I., Skov, T. W., Luo, Y., Dybkær, K. & Mikkelsen, J. G. (2023). Resistance to vincristine in DLBCL by disruption of p53-induced cell cycle arrest and apoptosis mediated by KIF18B and USP28. British Journal of Haematology, 202(4), 825-839. https://doi.org/10.1111/bjh.18872
Almeida Ferreira, S. R., Li, C., Klæstrup, I. H., Vitic, Z., Rasmussen, R. K., Kirkegaard, A., Toft, G. U., Betzer, C., Svendsen, P., Jensen, P. H., Luo, Y., Etzerodt, A., Moestrup, S. K. & Romero-Ramos, M. (2023). Sex-dimorphic neuroprotective effect of CD163 in an α-synuclein mouse model of Parkinson's disease. npj Parkinson's Disease , 9(1), 164. Article 164. https://doi.org/10.1038/s41531-023-00606-w
Cham, L. B., Gunst, J. D., Schleimann, M. H., Frattari, G. S., Rosas-Umbert, M., Vibholm, L. K., van der Sluis, R. M., Jakobsen, M. R., Olesen, R., Lin, L., Tolstrup, M. & Søgaard, O. S. (2023). Single cell analysis reveals a subset of cytotoxic-like plasmacytoid dendritic cells in people with HIV-1. iScience, 26(9), Article 107628. https://doi.org/10.1016/j.isci.2023.107628
Chen, D., Luo, Y. & Cheng, G. (2023). Single cell and immunity: Better understanding immune cell heterogeneities with single cell sequencing. Clinical and Translational Medicine, 13(1), Article e1159. https://doi.org/10.1002/ctm2.1159
Yang, S., Lan, T., Wei, R., Lin, L., Du, H., Huang, Y., Zhang, G., Huang, S., Shi, M., Wang, C., Li, R., Han, L., Tang, D., Li, H., Zhang, H., Cui, J., Lu, H., Huang, J., Luo, Y. ... Fang, S.-G. (2023). Single-nucleus transcriptome inventory of giant panda reveals cellular basis for fitness optimization under low metabolism. BMC Biology, 21(1), 222. Article 222. https://doi.org/10.1186/s12915-023-01691-2
Song, Q., Datta, S., Liang, X., Xu, X., Pavicic, P., Zhang, X., Zhao, Y., Liu, S., Zhao, J., Xu, Y., Xu, J., Wu, L., Wu, Z., Zhang, M., Zhao, Z., Lin, C., Wang, Y., Han, P., Jiang, P. ... Yang, J. (2023). Type I interferon signaling facilitates resolution of acute liver injury by priming macrophage polarization. Cellular & molecular immunology, 20(2), 143-157. https://doi.org/10.1038/s41423-022-00966-y
Ma, W., Zhong, X., Cai, B., Shao, M., Yu, X., Lv, M., Xu, S., Zhan, B., Li, Q., Ma, M., Kjær, M. B., Huang, J., Luo, Y., Grønbæk, H. & Lin, L. (2023). Unveiling the pathogenesis of non-alcoholic fatty liver disease by decoding biomarkers through integrated single-cell and single-nucleus profiles. https://doi.org/10.1101/2023.10.05.23296635
Jovic, D., Yu, Y., Wang, D., Wang, K., Li, H., Xu, F., Liu, C., Liu, J. & Luo, Y. (2022). A Brief Overview of Global Trends in MSC-Based Cell Therapy. Stem Cell Reviews and Reports, 18(5), 1525-1545. https://doi.org/10.1007/s12015-022-10369-1
Andersen, O. M., Bøgh, N., Landau, A. M., Pløen, G. G., Jensen, A. M. G., Monti, G., Ulhøi, B. P., Nyengaard, J. R., Jacobsen, K. R., Jørgensen, M. M., Holm, I. E., Kristensen, M. L., Alstrup, A. K. O., Hansen, E. S. S., Teunissen, C. E., Breidenbach, L., Droescher, M., Liu, Y., Pedersen, H. S. ... Sørensen, C. B. (2022). A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency. Cell Reports Medicine, 3(9), Article 100740. https://doi.org/10.1016/j.xcrm.2022.100740
Wang, F., Ding, P., Liang, X., Ding, X., Brandt, C. B., Sjöstedt, E., Zhu, J., Bolund, S., Zhang, L., de Rooij, L. P. M. H., Luo, L., Wei, Y., Zhao, W., Lv, Z., Haskó, J., Li, R., Qin, Q., Jia, Y., Wu, W. ... Luo, Y. (2022). Author Correction: Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level (Nature Communications, (2022), 13, 1, (3620), 10.1038/s41467-022-31388-z). Nature Communications, 13(1), Article 6748. https://doi.org/10.1038/s41467-022-34498-w
Lv, W., Pan, X., Han, P., Wang, Z., Feng, W., Xing, X., Wang, Q., Qu, K., Zeng, Y., Zhang, C., Xu, Z., Li, Y., Zheng, T., Lin, L., Liu, C., Liu, X., Li, H., Henriksen, R. A., Bolund, L. ... Luo, Y. (2022). Circle-Seq reveals genomic and disease-specific hallmarks in urinary cell-free extrachromosomal circular DNAs. Clinical and Translational Medicine, 12(4), Article e817. https://doi.org/10.1002/ctm2.817
Jager, S. E., Pallesen, L. T., Lin, L., Izzi, F., Pinheiro, A. M., Villa-Hernandez, S., Cesare, P., Vaegter, C. B. & Denk, F. (2022). Comparative transcriptional analysis of satellite glial cell injury response. Wellcome Open Research, 7, Article 156. https://doi.org/10.12688/wellcomeopenres.17885.1
Corsi, G. I., Qu, K., Alkan, F., Pan, X., Luo, Y. & Gorodkin, J. (2022). CRISPR/Cas9 gRNA activity depends on free energy changes and on the target PAM context. Nature Communications, 13(1), Article 3006. https://doi.org/10.1038/s41467-022-30515-0
Wang, F., Ding, P., Liang, X., Ding, X., Brandt, C. B., Sjöstedt, E., Zhu, J., Bolund, S., Zhang, L., de Rooij, L. P. M. H., Luo, L., Wei, Y., Zhao, W., Lv, Z., Haskó, J., Li, R., Qin, Q., Jia, Y., Wu, W. ... Luo, Y. (2022). Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level. Nature Communications, 13(1), Article 3620. https://doi.org/10.1038/s41467-022-31388-z
Noer, J. B., Hørsdal, O. K., Xiang, X., Luo, Y. & Regenberg, B. (2022). Extrachromosomal circular DNA in cancer: history, current knowledge, and methods. Trends in Genetics, 38(7), 766-781. https://doi.org/10.1016/j.tig.2022.02.007
Karlsson, M., Sjöstedt, E., Oksvold, P., Sivertsson, Å., Huang, J., Álvez, M. B., Arif, M., Li, X., Lin, L., Yu, J., Ma, T., Xu, F., Han, P., Jiang, H., Mardinoglu, A., Zhang, C., von Feilitzen, K., Xu, X., Wang, J. ... Uhlen, M. (2022). Genome-wide annotation of protein-coding genes in pig. BMC Biology, 20, Article 25. https://doi.org/10.1186/s12915-022-01229-y
Pan, X., Qu, K., Yuan, H., Xiang, X., Anthon, C., Pashkova, L., Liang, X., Han, P., Corsi, G. I., Xu, F., Liu, P., Zhong, J., Zhou, Y., Ma, T., Jiang, H., Liu, J., Wang, J., Jessen, N., Bolund, L. ... Luo, Y. (2022). Massively targeted evaluation of therapeutic CRISPR off-targets in cells. Nature Communications, 13(1), Article 4049. https://doi.org/10.1038/s41467-022-31543-6
Li, Z., Sun, C., Wang, F., Wang, X., Zhu, J., Luo, L., Ding, X., Zhang, Y., Ding, P., Wang, H., Pu, M., Li, Y., Wang, S., Qin, Q., Wei, Y., Sun, J., Wang, X., Luo, Y., Chen, D. & Qiu, W. (2022). Molecular mechanisms governing circulating immune cell heterogeneity across different species revealed by single-cell sequencing. Clinical and Translational Medicine, 12(1), Article e689. https://doi.org/10.1002/ctm2.689
Geldhof, V., de Rooij, L. P. M. H., Sokol, L., Amersfoort, J., De Schepper, M., Rohlenova, K., Hoste, G., Vanderstichele, A., Delsupehe, A. M., Isnaldi, E., Dai, N., Taverna, F., Khan, S., Truong, A. C. K., Teuwen, L. A., Richard, F., Treps, L., Smeets, A., Nevelsteen, I. ... Carmeliet, P. (2022). Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast. Nature Communications, 13, Article 5511. https://doi.org/10.1038/s41467-022-33052-y
Jovic, D., Liang, X., Zeng, H., Lin, L., Xu, F. & Luo, Y. (2022). Single-cell RNA sequencing technologies and applications: A brief overview. Clinical and Translational Medicine, 12(3), Article e694. https://doi.org/10.1002/ctm2.694
Li, C., Zhang, Y., Leng, L., Pan, X., Zhao, D., Li, X., Huang, J., Bolund, L., Lin, G., Luo, Y. & Xu, F. (2022). The single-cell expression profile of transposable elements and transcription factors in human early biparental and uniparental embryonic development. Frontiers in Cell and Developmental Biology, 10, Article 1020490. https://doi.org/10.3389/fcell.2022.1020490
Kostanjšek, R., Diderichsen, B., Recknagel, H., Gunde-Cimerman, N., Gostinčar, C., Fan, G., Kordiš, D., Trontelj, P., Jiang, H., Bolund, L. & Luo, Y. (2022). Toward the massive genome of Proteus anguinus-illuminating longevity, regeneration, convergent evolution, and metabolic disorders. Annals of the New York Academy of Sciences, 1507(1), 5-11. https://doi.org/10.1111/nyas.14686
Koning, M., Dumas, S. J., Avramut, M. C., Koning, R. I., Meta, E., Lievers, E., Wiersma, L. E., Borri, M., Liang, X., Xie, L., Liu, P., Chen, F., Lin, L., Luo, Y., Mulder, J., Spijker, H. S., Jaffredo, T., van den Berg, B. M., Carmeliet, P. ... Rabelink, T. J. (2022). Vasculogenesis in kidney organoids upon transplantation. npj Regenerative Medicine, 7(1), Article 40. https://doi.org/10.1038/s41536-022-00237-4
Liu, X., Xu, Y., Wang, R., Liu, S., Wang, J., Luo, Y., Leung, K.-S. & Cheng, L. (2021). A network-based algorithm for the identification of moonlighting noncoding RNAs and its application in sepsis. Briefings in bioinformatics, 22(1), 581-588. https://doi.org/10.1093/bib/bbz154
Huang, J., Lin, L., Dong, Z., Yang, L., Zheng, T., Gu, W., Zhang, Y., Yin, T., Sjöstedt, E., Mulder, J., Uhlén, M., Kristiansen, K., Bolund, L. & Luo, Y. (2021). A porcine brain-wide RNA editing landscape. Communications Biology, 4(1), 717. Article 717. https://doi.org/10.1038/s42003-021-02238-3
Wang, F., Xu, Q., Zhuang, Z., Li, Z., Gao, Q., Huang, Y., Luo, Y., Zhang, X., Zhu, L. & Chao, C.-C. (2021). A single-cell approach to engineer CD8+ T cells targeting cytomegalovirus. Cellular & molecular immunology, 18, 1326-1328. https://doi.org/10.1038/s41423-020-0466-z
Karlsson, M., Zhang, C., Méar, L., Zhong, W., Digre, A., Katona, B., Sjöstedt, E., Butler, L., Odeberg, J., Dusart, P., Edfors, F., Oksvold, P., von Feilitzen, K., Zwahlen, M., Arif, M., Altay, O., Li, X., Ozcan, M., Mardonoglu, A. ... Lindskog, C. (2021). A single-cell type transcriptomics map of human tissues. Science Advances, 7(31), Article eabh2169. https://doi.org/10.1126/sciadv.abh2169
Banerjee, S., Zhang, X., Kuang, S., Wang, J., Li, L., Fan, G., Luo, Y., Sun, S., Han, P., Wu, Q., Yang, S., Ji, X., Li, Y., Deng, L., Tian, X., Wang, Z., Zhang, Y., Wu, K., Zhu, S. ... Liu, X. (2021). Comparative analysis of clonal evolution among patients with right- and left-sided colon and rectal cancer. iScience, 24(7), Article 102718. https://doi.org/10.1016/j.isci.2021.102718
Xiang, X., Zhao, X., Pan, X., Dong, Z., Yu, J., Li, S., Liang, X., Han, P., Qu, K., Jensen, J. B., Farup, J., Wang, F., Petersen, T. S., Bolund, L., Teng, H., Lin, L. & Luo, Y. (2021). Efficient correction of Duchenne muscular dystrophy mutations by SpCas9 and dual gRNAs. Molecular Therapy - Nucleic Acids, 24, 403-415. https://doi.org/10.1016/j.omtn.2021.03.005
Xiang, X., Corsi, G. I., Anthon, C., Qu, K., Pan, X., Liang, X., Han, P., Dong, Z., Liu, L., Zhong, J., Ma, T., Wang, J., Zhang, X., Jiang, H., Xu, F., Liu, X., Xu, X., Wang, J., Yang, H. ... Luo, Y. (2021). Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning. Nature Communications, 12(1), Article 3238. https://doi.org/10.1038/s41467-021-23576-0
Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G., Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H. ... Jessen, N. (2021). Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients. Cell Metabolism, 33(11), 2201-2214.e10. https://doi.org/10.1016/j.cmet.2021.10.001
Andersen, O. M., Bøgh, N., Landau, A., Pløen, G. G., Jensen, A. M. G., Monti, G., Ulhøi, B. P., Nyengaard, J. R., Jacobsen, K. R., Jørgensen, M. M., Holm, I. E., Kristensen, M. L., Søvsø Szocska Hansen, E., Teunissen, C. E., Breidenbach, L., Droescher, M., Liu, Y., Pedersen, H. S., Callesen, H. ... Sørensen, C. B. (2021). In vivo evidence that SORL1, encoding the endosomal recycling receptor SORLA, can function as a causal gene in Alzheimer´s Disease. http://biorxiv.org/content/early/2021/07/13/2021.07.13.452149
Dumas, S. J., Meta, E., Borri, M., Luo, Y., Li, X., Rabelink, T. J. & Carmeliet, P. (2021). Phenotypic diversity and metabolic specialization of renal endothelial cells. Nature Reviews. Nephrology, 17(7), 441-464. https://doi.org/10.1038/s41581-021-00411-9
Link to full publications at PURE