Introduction of PigX

The aim of this international xenotransplantation phenotyping and development project (PigX) is to better understand the immune rejection of xenograft at molecular and cellular levels using the latest single cell RNA sequencing and spatial transcriptomics technologies. This project is led by associate professor Lin Lin from the DREAM team and supported by the the Danish Research Council for Independent Research and the Nono Nordisk Foundation.

PigX research consortium

Asso. Prof. Lin Lin, Associate Professor, Department of Biomedicine, Aarhus University; Steno Diabetes Center Aarhus, AUH, Aarhus, Denmark. Gene editing, Single cell RNA sequencing, Spatial Transcriptomics
Prof. Dr. Angelika E. Schnieke, Professor, TUM School of Life Sciences, Technical University of Munich, Munich, Germany. Animal biotechnology, xenotransplantation
Prof. Dr. Ton Rabelink, Professor, Leiden University Medical Center, The Netherlands. Nephrology, kidney transplantation.
Asso. Prof. Yonglun Luo (Alun), Associate Professor, Department of Biomedicine, Aarhus University; Steno Diabetes Center Aarhus, AUH, Aarhus, Denmark. Lars Bolund Institute of Regenerative Medicine, BGI-Research, China. CRISPR gene editing, Stem cell technology, Regenerative Medicine, OMICS

Single cell RNA sequencing of kidney endothelial cells

Single Cell RNA sequencing of human PBMCs

Single Cell RNA sequencing of pig kidney influx cells